Shien Hu Selected Research

Muscarinic M3 Receptor

1/2021	Overcoming Obstacles to Targeting Muscarinic Receptor Signaling in Colorectal Cancer.
3/2019	The Role of M3 Muscarinic Receptor Ligand-Induced Kinase Signaling in Colon Cancer Progression.
1/2018	Targeting M3 Muscarinic Receptors for Colon Cancer Therapy.
1/2017	Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells.

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Shien Hu Research Topics

Disease

12	Colonic Neoplasms (Colon Cancer) 01/2022 - 01/2009
7	Neoplasms (Cancer) 01/2022 - 01/2009
5	Inflammation (Inflammations) 04/2011 - 12/2007
3	Carcinogenesis 10/2015 - 01/2009
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/2011 - 12/2010
1	Colorectal Neoplasms (Colorectal Cancer) 01/2021
1	Persistent Infection 12/2020
1	Amyloidosis 12/2020
1	Autoimmune Diseases (Autoimmune Disease) 12/2020
1	Hematemesis 12/2020
1	Nausea 12/2020
1	Ulcer 12/2020
1	Renal Insufficiency (Renal Failure) 12/2020
1	Aberrant Crypt Foci 10/2015
1	Colitis 05/2009
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2009

Drug/Important Bio-Agent (IBA)

6	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 01/2022 - 01/2017
4	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2022 - 01/2017
4	Muscarinic M3 ReceptorIBA 01/2021 - 01/2017
4	Proteins (Proteins, Gene)FDA Link 03/2019 - 05/2009
3	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2011
3	p38 Mitogen-Activated Protein KinasesIBA 01/2022 - 01/2017
3	Phosphotransferases (Kinase)IBA 03/2019 - 10/2015
3	Messenger RNA (mRNA)IBA 03/2019 - 05/2009
3	CytokinesIBA 04/2011 - 12/2007
3	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 04/2010 - 01/2009
2	Biological ProductsIBA 12/2021 - 01/2018
2	Matrix Metalloproteinases (MMPs)IBA 01/2021 - 03/2019
2	Mitogen-Activated Protein KinasesIBA 03/2019 - 01/2017
2	Bile Acids and Salts (Bile Acids)IBA 03/2019 - 10/2015
2	Cholinergic Agents (Cholinergics)IBA 03/2019 - 10/2015
2	Butyrates (Butyrate)IBA 10/2015 - 01/2011
2	Dextran SulfateIBA 10/2015 - 01/2009
2	AzoxymethaneIBA 10/2015 - 01/2009
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 12/2010 - 12/2007
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2010 - 12/2007
1	Rho Guanine Nucleotide Exchange FactorsIBA 01/2021
1	AA amyloidosisIBA 12/2020
1	Protein Kinase CIBA 03/2019
1	LigandsIBA 03/2019
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 03/2019
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 03/2019
1	Protein Kinases (Protein Kinase)IBA 03/2019
1	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 01/2017
1	Epidermal Growth Factor (EGF)IBA 01/2017
1	Valproic Acid (Depakote)FDA LinkGeneric 10/2015
1	Vorinostat FDA Link 10/2015
1	Dietary Fiber FDA Link 10/2015
1	Histone Deacetylase InhibitorsIBA 10/2015
1	CarcinogensIBA 10/2015
1	ErbB Receptors (EGF Receptor)IBA 10/2015
1	human SLC22A5 proteinIBA 04/2011
1	Volatile Fatty AcidsIBA 01/2011
1	Interferon-gamma (Interferon, gamma)IBA 04/2010
1	Dextrans (Dextran)FDA Link 05/2009
1	villinIBA 05/2009
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 05/2009
1	Untranslated Regions (Untranslated Region)IBA 05/2009
1	3' Untranslated Regions (3' UTR)IBA 05/2009
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2009
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2009
1	beta CateninIBA 01/2009

Therapy/Procedure

3	Therapeutics 01/2021 - 01/2018